Coordinator: University of Bologna
Scientific Officer: Stefano Tartarini
Duration: 12/10/2023 - 12/10/2025
Research group: Stefano Tartarini (University of Bologna), Filippo Geuna (University of Milan), Angelantonio Minafra (CNR).
A major Sharka resistance determinant (PPVres) has been identified on chromosome 1 in apricot. Following the comparison of the ‘Resistant’ and ‘Susceptible’ haplotypes of the PPVres region, some candidate genes have been identified. The project develops over the following main objectives: (a) development of a dense linkage map and QTL analysis on a large available progeny; (b) identification of candidate genes and markers tightly associated in a panel of resistant genotypes; (c) combined analysis of ‘Lito’ transcriptome and small RNAs to disclose the differential gene expression and silencing effect during PPV infection; (d) validation of candidate genes by genetic transformation, genome editing and virus-induced gene silencing.