MASTITOMIC

Host – microbiota interactions in the homeostasis of the bovine mammary gland ecosystem: the mastitis model

Coordinator: Università degli Studi di Padova, Dipartimento di Agronomia Animali Alimenti Risorse Naturali e Ambiente - DAFNAE

Scientific officer: Martina Zappaterra

Duration: 30/11/2023 - 30/11/2025

Research group: Martina Zappaterra, Leonardo Nanni Costa, Barbara Padalino.

Bovine mastitis has been associated with substantial economic losses and increased development of antimicrobial-resistant strains. MASTITOMIC project arises from the hypothesis that subclinical mastitis may occur from a mammary gland dysbiosis and thus the project aims i) to characterize the evolution of host-microbiota interaction; ii) to assess the role of host genetics, environmental factors, and mammary microbiota in mastitis infection; iii) to find risk factors associated with mastitis occurrence. The joint analysis of data will allow to evaluate the feasibility of sensors for early detection of mastitis infection in dairy cattle and will provide an unprecedented insight into host-microbiome interac-tion in healthy and mastitic cows.